Micky van de Ven Double Halts Everton's Run at Brand New Stadium
The Dutch defender emerged as the first defender to net two goals in a English top-flight match for Tottenham since Jan Vertonghen in March 2013.
Key points
The Spurs defender nods into the net twice in opening period
The home side's defender has goal disallowed after video check
Senegalese midfielder scores final goal in 89th minute
This loss is Everton's first at Hill Dickinson Stadium
Micky van de Ven found the net twice as Tottenham prolonged their winning streak in away games in the Premier League and handed Everton their first defeat at their new home.
The Toffees were unbeaten in their last five matches at their new ground at Bramley-Moore Dock, having departed Goodison Park behind after more than a century at the conclusion of last season.
But Spurs captain Van de Ven struck twice from set-pieces in the opening 45 minutes to put their strong form at jeopardy, and they were failed to turn it around before Pape Matar Sarr - assisted by ex-Everton forward the Brazilian - nodded in a final goal to put the game to bed.
Jake O'Brien believed he had equalized the tally five minutes after Van de Ven's opener, directing a powerful header past the Spurs keeper from an Everton corner.
Beto, meanwhile, failed to convert a number of chances, while the Italian goalkeeper made a series of excellent saves to ensure the London club went five matches on the road unbeaten in the English top flight.
But the video assistant referee stepped in, instructing the match official to review the score on the screen and the referee ruled that Jack Grealish and Iliman Ndiaye were in an illegal position and had interfered with the Tottenham goalkeeper.
The win elevates Thomas Frank's team into third place in the division, a handful of points off north London rivals and table-toppers the Gunners.
The Merseyside club stay 14th and sit six points ahead of the relegation zone.
Spurs breakdown: Van de Ven fulfils duties at each end of pitch
Following a uninspiring weekday display in the Champions League against the French side, where they mustered a mere two shots on target, the manager chose Randal Kolo Muani up front instead of ex-Everton forward Richarlison.
The summer signing was unable to influence the game before being substituted for Richarlison after 60 minutes on the field, but it emerged he proved unnecessary in the final outcome.
Defender the Dutchman converted into an attacking force to be feared.
Tottenham's first goal came from a well-worked set-piece play, with Rodrigo Bentancur directing the ball toward the face of goal for an free Van de Ven to head home.
And the captain - filling in as skipper in Cristian Romero's unavailability - added his next goal in added time as he rose above the England keeper to nod in.
The Dutchman was equally impressive in defensive duties, partnering effectively with Kevin Danso as the pair dealt excellently with the 34 crosses thrown their way by Everton.
Everton analysis: Everton lacking striker's instinct
The club's new home had been a happy hunting ground, but it seems the freshness may have worn off slightly and supporters flocked to the gates after Sarr's third for Spurs.
The end in Everton's unbeaten home run will not be a massive worry for David Moyes, but their striker situation will be.
Beto and Thierno Barry - the Everton's pair of recognised strikers - had scored only one league goal between them before Sunday's outing.
And they were failed to contribute to that poor record on a wet and gloomy night on Merseyside.
Beto's form was epitomized when he opted to overhead kick a golden opportunity from close range, even with having space and time to reposition for a more conventional shot that would have tested the keeper.
Barry, as well, was unable to influence the game after coming on for Beto in the 65th minute.
It was not for a shortage of opportunity. Most of the home side's offensive moves came through the winger and Ndiaye, who tirelessly delivered dangerous crosses into the Tottenham box.
What next for both teams?
Everton: The team head to Sunderland in the Premier League on Monday, 3 November at 20:00 GMT.
Spurs: Spurs travel to Newcastle's ground on Wednesday, 29 October for their next round League Cup tie against Newcastle.